Karkat and his friends and everyone they would ever meet thereafter would experience great misfortune on account of the curse unwittingly implemented through Sollux's esoteric MOBIUS DOUBLE REACHAROUND VIRUS.
Every troll's lusus would soon die. All but one of their kernelsprites would be prototyped with a dead lusus, each prior to entering the Medium. Upon entry, they would each have a bittersweet reunion with the creature after the kernel hatched, triggering the sprite's metamorphosis. For the first time, the trolls would be able to have verbal conversations with their custodians, and would be guided by them along their journeys.
Unfortunately, the underlings and warring royalty would gain the benefits of the monstrous prototypings as well. Each sprite, except for one, would only be prototyped once. The players would learn quickly that while one pre-entry prototyping per player was absolutely necessary for ultimate success, additional pre-entry prototypings merely empowered their enemies unnecessarily.